Materials glossary / Standard and mark
Nickel allergy
On the label: Nickel allergy · Standard and mark
What it is
The most common contact allergy: about 10 to 20 percent of women and a few percent of men react to nickel with an itchy rash where metal touches skin. Caused by nickel released from alloys and base metals, especially under plating that has worn.
Standard and marks: The marks, tests and laws behind the words on a label: karat stamps, UV400, ANSI Z80.3, the FTC Jewelry Guides, Prop 65.
Wikidata: Allergic contact dermatitis that has allergic trigger nickel atom. Q16606544 →
In the research
720 PubMed papers mention it with jewelry, allergy, eyewear or UV; the three most recent:
- Fully biodegradable ventricular septal defect occluders: from biomaterials to clinical translation · Cardiovascular intervention and therapeutics, 2026
- Patch Test Relevance and Systemic Exposure Pathways in Eczema Patterns Suspected of Systemic Contact Dermatitis · Contact dermatitis, 2026
- Reverse pedicle subtraction osteotomy for iatrogenic hyperlordosis in a scoliosis patient: illustrative case · Journal of neurosurgery. Case lessons, 2026
A paper is a paper, not a verdict: titles are listed so you can read them, and a study on one fabric or one filter says little about the piece in your hand.
Other standard and marks
Clasp & Lens describes materials from the public record and does not appraise, grade or test pieces; what a listing states is the supplier's statement. If a piece causes a rash, take it off; a reaction that spreads or blisters is a doctor's question, and sunglasses are no substitute for impact-rated eye protection where that is required.